Prepared by Mark Miller, MD, Fellow, Department of Medicine, Division of Infectious Diseases,Los Angeles County/University of Southern California Medical Center, Los Angeles, Calif

A 21-year-old white man presented to the emergency department with a maculopapular eruption on his palms (Figure 1). Physical examination revealed other lesions on his trunk and lower extremities (Figure 2) but no oral lesions. The lesions were neither painful nor pruritic. He had fever, headache, and malaise and reported that he had been diagnosed with acute hepatitis B infection 1 month earlier.

What's Your Diagnosis?

• Erythema multiforme major
• Syphilis
• Sweet's syndrome
• Pustular psoriasis